SPOILER SPOILER SPOILER
Saddest Moments in a game
1) Death of Henry (Mafia II, I cried when this happened)
2) Death of Carlos (Saints Row 2, a definite WTF moment)
3) Death of Franky "Beans'' LaRoche (Brothers in Arms Hells Highway, he was really like only 15 years old, but he lied about his age, so once you find out he was really young, that makes it even sadder)
Those are my ''Saddest Moments''.