To play multiplayer in Resident Evil 6, you must complete the single player prelude first. You have no choice since it automatically enters into it. Once you complete the prelude which is the first mission. You can choose the campaign you wish to play with and than on the screen option, you switch it to split which is the multiplayer. Single screen is single player. Hopefully this answers your question. Hopefully everyone enjoys resident evil 6 because I am. Time to kick zombie butt.