If you've played Civ on the PC, then this will be pretty easy for you. They've simplified many aspects of the game. Also due to it being on a console it takes a while longer to move around find what you're looking for then it does on a PC with a mouse.
It's pretty fun though. It's easy enough that you can sit down and play for a few hours without having to remember what every city and every unit is doing. Then when you're done save the game and come back to it later. No sweat.
I'm an old fan of the Civilization games on the PC so I was excited to see this game come along.
If you've never played Civ before, most of what I'm about to say won't affect you. If you're an old salt to the game like myself, this might make a difference.
The game doesn't have the same level of control the PC version has. A lot of the functions are either missing or are automated for you. Things like building roads is completely different. There's no option to alter land squares from say swap to grasslands. You can't change the population from farmers to entertainers to control riots and such.
Where it would take days sometimes to complete a game on the PC, I can easily finish a game on the PS3 in a couple of hours. The lack of macro level control over the minutia really speeds things up. But to be honest, I liked having the added control in the PC game.
I've not been able to successfully connect to an online server for head-to-head play. It never seems to work. This is something that's really annoying and keeps me from giving it a 10.
The animation sequences get a little annoying, I would like the ability to turn them all off, but that's a minor point.
Over all I would say this is a great port to the PS3 (and Xbox) and have gotten lots of play time out of the game. I actually decided to buy it, I don't do that often.