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Free Ammo and Health
Go to any challenge like Annihilation Nation, start the challenge and quit and it refills your ammo and health.
Free weapons.
Although you can buy any of these weapons during the game, you can get them free from Slim Cognito on Aquatos at certain times in the game if you have a Ratchet & Clank:Going Commando save file on your memory card. The weapons are, Miniturret Glove, Lava Gun, Shield Charger, Bouncer, and Plasma Coil.
Get a discount on weapons
If you have a save from Ratchet and Clank 1, you get a 10% discount on weapons when you buy them. Save must be past the 2nd hoverboard race.
Re-play completed Hacker puzzles
To re-play a completed Hacker puzzle: Stand in front of it, hold R1, then press Triangle.
Skip Quark vidcomics
Go to the game system on Starship Phoenix with a vidcomic that you haven't beaten yet. Now select the level of the unplayed vidcomic. Scroll up to the first one and press Up again. If it's the fifth vidcomic then press Up yet again. As long as from the first vidcomic you get back to selecting the latest unplayed vidcomic, press X to play. The game prompts to skip the level. Agreeing will finish the level with no records. In Challenge Mode, it will show no records EXCEPT the best time you got during your first try in the game.