New parents Mac (Seth Rogan) and Kelly Radner (Rose Byrne) have settled into an idyllic life in their comfortable suburban home. Their routine existence gets upended, however, when a group of rowdy Delta Psi Beta frat boys led by Teddy Sanders (Zac Efron) move in next door. Still clinging to the belief that they have yet to turn into thirty-something squares, Mac and Kelly try to get along with their new neighbors. Until they decide that the partying lifestyle is too much for them...and too loud. Finally drawing a line in the neighborly sand, the Radners start a turf war of escalating sabotage against the young fraternity in this raunchy new comedy from director Nicholas Stoller (Forgetting Sarah Marshall).