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Glitches brought to you by 
Body full of crossbow bolts
When fighting The Fear, before you beat him, let him hit you a few times with his crossbow. The bolts will stay in your body, and you are supposed to remove them through the Cure menu. If you beat him, you will automatically be healed fully, but the bolts will still be stuck in you for the rest of the game. If you go to your Cure menu, you will see them sticking out of you, but you can't remove them. They are visible with any camo you wear, but not visible during cutscenes.
No Damage Through Torture
Hold L2 during the entire torture sequence to not recieve any damage when Volgin punches you. It must remain held down until cutscene where he leaves otherwise any damage that would have been done is still dealt.
Tight Space GLITCH.
First equip the binoculars, then quick unequip.
Enter a tight space, like a vent, and as SOON as the camera begins to move into 'Intrusion Mode' aka First Person immediatly equip the binoculars. You will continue to move forward WITH the binoculars equiped, but you will not be able to control Snake at all, except to unequip the binoculars, which will then return everything to normal.