| EA SPORTS ALL-PLAY OFFENSIVE CONTROLS: | |
| |  | | Control Pad | | Move. Left/Right = Switch Controlled Player (Co-op Only). |
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|  | | A Button | | Snap Ball. Stiff Arm. Juke. Spin. No Huddle (Hold). |
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|  | | B Button | | Coach Cam (Hold). Stiff Arm. Juke. Spin. Spike Ball (Hold). |
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| | Throw Ball (Flick Lightly for Lob, Flick Quickly for Bullet) | | | | Point and Pass (Tap for Lob, Hold for Bullet) | | | | Throw Ball Away | | Hold C Button and flick Wii Remote or point off screen and hit A Button. | | | Power Move | | | | Break Tackle | | | | Catch Ball | | |
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| EA SPORTS ALL-PLAY DEFENSIVE CONTROLS: | |
| | | Sack the QB. Stop the Run. Defend the Pass. | | | | Switch Controlled Player | | | | Big Hit. Swat Ball. | | | | Low Hit | | | | Jump. Intercept. | | | | Rip. Swim. Spin. | | |
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| GENERAL ADVANCED OFFENSIVE CONTROLS: | |
|  | | Control Pad | | Left/Right = Switch Controlled Player |
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| |  | | B Button | | Quick QB Audibles |
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| | Pre-Play Menu | | | | Lock On (Directional Passing Only) | | |
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| ADVANCED OFFENSIVE CONTROLS (QB CONTROLS): | |
| | |  | | C Button | | Dive (Hold). QB Slide (Tap). |
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| | Throw Ball | | | | Lock On | | | | Precision Passing | | | | Throw Ball Away | | Hold Z Button and flick Wii Remote down or point Wii Remote off screen and hit A Button. | | | QB Avoidance | | |
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| ADVANCED OFFENSIVE CONTROLS (RUNNING, CATCHING, AND BLOCKING): | |
| |  | | Control Pad | | Left/Right = Stiff Arm |
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| | Directional Juke | | | | Power Move | | | | Break Tackles | | | | Catch Ball | | | | Impact Block | | | | Cut Block | | |
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| ADVANCED OFFENSIVE CONTROLS (AFTER THE PLAY): | |
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| ADVANCED DEFENSIVE CONTROLS (BEFORE THE SNAP): | |
|  | | B Button | | Quick LB Audibles |
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| | Pre-Play Menu | | | | Switch Controlled Player | | |
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| ADVANCED DEFENSIVE CONTROLS (DURING THE PLAY): | |
| |  | | Control Pad | | Up = Pass Commit. Strip Ball. Down = Run Commit. |
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|  | | A Button | | Control Defender Nearest Ball |
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| | Big Hit. Rip. Swim. Spin. | | | | Low Hit | | | | Swat | | | | Jump. Intercept. | | |
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| | | Kick Ball | | Hold Wii Remote down at the ground, hold A Button, then swing Wii Remote up to gain power and kick ball. | | | Fair Catch | | Hold Wii Remote up and wave left and right. | |
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