I really enjoy the show. This game is not the best but it is not horrible either. The graphics are not very good but if you could careless about the graphics then its fine. The game play is a little wacky but, the characters mimic the characters on the show. The best part of the mini games is by far the surgeries. The rest of the mini games are all basically the same and get very boring after a while. This game is basically pointing at the screen and pressing the "a." The characters are designed to fit their true human form. Some are very close like Bailey or Erica. Some are just poor designing though. The dialogue between the cast of the game shows the personality we see on the show.
I would suggest this game if you just want to have fun, a game you play every once and awhile and not to beat in just one night. Yes the design of the game is not very good but for some that doesn't matter. I would give this game a try.
Though the game is mostly like the tv show, there isn't as much medical stuff in it as I expected. I only played through 5 scenes but you actually are a character on the tv show and you have to make choices should I go on a date with so and so or not there is no right or wrong answer. But that part is kind of lame. The medical aspect of the game is interesting you get to make incision using your wii remote and also make sutures which was kind of cool.