Not only does this game work perfectly (windows 7 i5 64 bit) but its an amazing game worth the time to play.
Anyone having a problem installing games from here needs to understand how to set compatibility mode (xp service pack 2 is reliable) and also needs to know WHICH FILE TO SET COMPATIBILITY MODE ON!!!!!
Usually its the "setup.exe" file that is in the folder the game downloaded to ( usually in the "gamefly" folder in your users directory)
if any of this is too complicated for you... well, that sucks... you're missing out on a great game.
I also recommend playing this with a gamepad/controller... Personally i use "motionjoy" to make my PS3 controller work on my PC.
Error came up after install when I tried playing it. I unintalled it and re-downloaded it and all that jazz and still the same error. Tomb Raider: Anniversary gave me the same error. Missing a certain file. I troubleshooted it for awhile and just gave up.