I will start by saying if you own a PS3 and have not played any of the Uncharted games then you are missing out on some of the best storytelling of this generation in gaming.
Pros- Amazing storytelling that is mostly unmatched by other games, graphics set the standards pretty high as they are just gorgeous and realistic, controls are easy enough to understand, included multiplayer and have now done away with online pass, free now for PS Plus subscribers, and I could keep going on but this game is just astounding (please take my word for it).
Cons- If I had to name any cons it would probably be at times the story did make you suspend a bit of disbelief even though the graphics and many other historical aspects are very realistic. Also I personally didn't find much to love with the multiplayer but didn't hate it either and this is a game that can stand on single player alone.
Overall: I give this game a 9/10 and that is rare for me to give as I hardly even want to give as high as an 8 for games today. This game and the rest in the series are what makes Sony's exclusives so desirable and make them the prized treasures of the PS3. This is a definite buy and I recommend it to even the most casual gamer!